The short answer is “probably.” And I encourage you to give it a try. StartOS is a 1GB download. If you are familiar with installing Linux, the install process will probably take you about as long as it took to write the question. Or at least, less time than it took you to get an answer.
Here’s our user reported master good hardware list:
Here’s the link to the instructions:
Keep in mind that a HDD is too slow to run a Bitcoin stack. But the upgrade process to transfer to a SSD later is easy.